This illness is the result of unusual blood flow. Blood from the digestive tract circumvents the liver, which cleanses toxins from the blood. These toxins can lead to other diseases, like severe liver disease. Portosystemic shunts usually happen in combination with other conditions. Symptoms include loss of appetite, poor balance, lethargy, depression, blindness, weakness, disorientation, seizures, and coma. Treatment includes surgery and a change in diet.